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Necrosing livedo reticularis in a patient with recurrent pulmonary hemorrhage

Identifieur interne : 002927 ( Main/Exploration ); précédent : 002926; suivant : 002928

Necrosing livedo reticularis in a patient with recurrent pulmonary hemorrhage

Auteurs : David M. Aronoff ; Jeffrey P. Callen

Source :

RBID : ISTEX:42DFCB9B3F3D6AD387870001483C1528BA44C59E

English descriptors

Abstract

Abstract: The antiphospholipid antibody (APS) syndrome is characterized by antiphospholipid antibodies (lupus anticoagulant [LA] or anticardiolipin [aCL], a recurrent arterial and venous thrombosis, recurrent fetal loss, and thrombocytopenia. Pulmonary hemorrhage is an unusual complication. We describe a 32-year-old woman with a history of recurrent pulmonary hemorrhage and transient renal dysfunction. Her original diagnosis was Goodpasture’s syndrome, and she was treated with immunosuppressive drugs. Necrosing livedo reticularis of the legs subsequently developed. The presence of aCL and LA in the patient’s serum, the finding of noninflammatory microthrombi in the dermal capillaries, and the lack of laboratory or pathologic features of Goodpasture’s syndrome, confirmed a diagnosis of APS in this patient. (J Am Acad Dermatol 1997;37:300-2.)

Url:
DOI: 10.1016/S0190-9622(97)80375-1


Affiliations:


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Le document en format XML

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<term>Alveolar hemorrhage</term>
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<term>Anticardiolipin</term>
<term>Anticoagulant</term>
<term>Antiphospholipid</term>
<term>Antiphospholipid antibodies</term>
<term>Antiphospholipid antibody syndrome</term>
<term>Biopsy specimen</term>
<term>Bland thrombi</term>
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<term>Chlorambucil</term>
<term>Cutaneous</term>
<term>Dermatol</term>
<term>Dermatology</term>
<term>Differential diagnosis</term>
<term>Hemorrhage</term>
<term>Hydroxychloroquine</term>
<term>Livedo</term>
<term>Livedo reticularis</term>
<term>Lower extremities</term>
<term>Lung hemorrhage</term>
<term>Lupus</term>
<term>Lupus anticoagulant</term>
<term>Necrosing</term>
<term>Necrosing livedo reticularis</term>
<term>Oral chlorambucil</term>
<term>Pulmonary capillaritis</term>
<term>Pulmonary emboli</term>
<term>Pulmonary hemorrhage</term>
<term>Renal</term>
<term>Reticularis</term>
<term>Rheumatol</term>
<term>Syndrome</term>
<term>Systemic lupus erythematosus</term>
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